14 best Python Genomics libraries in 2024

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by marketing.admin@openweaver.com dot icon Updated: Feb 2, 2023

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Python has become a primary language in the field of bioinformatics and computational biology. It is one of the best programming languages for scientific computing, data analysis, and analytics. It is also widely used by mathematicians and statisticians to create data-driven applications. The advent of next-generation sequencing technologies has enabled a revolution in genomic research. Python is also very popular in genomics and bioinformatics community due to the fact that it provides high level of abstraction, large number of available packages and great visualization tools. Genomics is a rapidly growing field with many new tools and techniques being developed every year. It can be used for various applications such as data analysis, statistical analysis, simulation and visualization. They have been tested on several different systems. A few of the most popular Python Genomics open source libraries for developers are: deepvariant - analysis pipeline that uses a deep neural network; hail - Scalable genomic data analysis; pyGenomeTracks - python module to plot beautiful.

deepvariantby google

Python doticonstar image 2819 doticonVersion:v1.5.0doticon
License: Permissive (BSD-3-Clause)

DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.

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            deepvariantby google

            Python doticon star image 2819 doticonVersion:v1.5.0doticon License: Permissive (BSD-3-Clause)

            DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.
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                      hailby hail-is

                      Python doticonstar image 881 doticonVersion:0.2.117doticon
                      License: Permissive (MIT)

                      Cloud-native genomic dataframes and batch computing

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                                hailby hail-is

                                Python doticon star image 881 doticonVersion:0.2.117doticon License: Permissive (MIT)

                                Cloud-native genomic dataframes and batch computing
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                                          pyGenomeTracksby deeptools

                                          Python doticonstar image 631 doticonVersion:3.8doticon
                                          License: Strong Copyleft (GPL-3.0)

                                          python module to plot beautiful and highly customizable genome browser tracks

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                                                    pyGenomeTracksby deeptools

                                                    Python doticon star image 631 doticonVersion:3.8doticon License: Strong Copyleft (GPL-3.0)

                                                    python module to plot beautiful and highly customizable genome browser tracks
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                                                              Python doticonstar image 759 doticonVersion:0.3.1doticon
                                                              License: Permissive (Apache-2.0)

                                                              Scripts to download genomes from the NCBI FTP servers

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                                                                        ncbi-genome-downloadby kblin

                                                                        Python doticon star image 759 doticonVersion:0.3.1doticon License: Permissive (Apache-2.0)

                                                                        Scripts to download genomes from the NCBI FTP servers
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                                                                                  jcviby tanghaibao

                                                                                  Python doticonstar image 587 doticonVersion:Currentdoticon
                                                                                  License: Permissive (BSD-2-Clause)

                                                                                  Python library to facilitate genome assembly, annotation, and comparative genomics

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                                                                                            jcviby tanghaibao

                                                                                            Python doticon star image 587 doticonVersion:Currentdoticon License: Permissive (BSD-2-Clause)

                                                                                            Python library to facilitate genome assembly, annotation, and comparative genomics
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                                                                                                      OrthoFinderby davidemms

                                                                                                      Python doticonstar image 549 doticonVersion:2.5.5doticon
                                                                                                      License: Strong Copyleft (GPL-3.0)

                                                                                                      Phylogenetic orthology inference for comparative genomics

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                                                                                                                OrthoFinderby davidemms

                                                                                                                Python doticon star image 549 doticonVersion:2.5.5doticon License: Strong Copyleft (GPL-3.0)

                                                                                                                Phylogenetic orthology inference for comparative genomics
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                                                                                                                          eggnog-mapperby eggnogdb

                                                                                                                          Python doticonstar image 461 doticonVersion:2.1.11doticon
                                                                                                                          License: Strong Copyleft (AGPL-3.0)

                                                                                                                          Fast genome-wide functional annotation through orthology assignment

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                                                                                                                                    eggnog-mapperby eggnogdb

                                                                                                                                    Python doticon star image 461 doticonVersion:2.1.11doticon License: Strong Copyleft (AGPL-3.0)

                                                                                                                                    Fast genome-wide functional annotation through orthology assignment
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                                                                                                                                              sourmashby sourmash-bio

                                                                                                                                              Python doticonstar image 368 doticonVersion:v4.8.2doticon
                                                                                                                                              License: Others (Non-SPDX)

                                                                                                                                              Quickly search, compare, and analyze genomic and metagenomic data sets.

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                                                                                                                                                        sourmashby sourmash-bio

                                                                                                                                                        Python doticon star image 368 doticonVersion:v4.8.2doticon License: Others (Non-SPDX)

                                                                                                                                                        Quickly search, compare, and analyze genomic and metagenomic data sets.
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                                                                                                                                                                  pyrangesby biocore-ntnu

                                                                                                                                                                  Python doticonstar image 340 doticonVersion:0.0.111doticon
                                                                                                                                                                  License: Permissive (MIT)

                                                                                                                                                                  Performant Pythonic GenomicRanges

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                                                                                                                                                                            pyrangesby biocore-ntnu

                                                                                                                                                                            Python doticon star image 340 doticonVersion:0.0.111doticon License: Permissive (MIT)

                                                                                                                                                                            Performant Pythonic GenomicRanges
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                                                                                                                                                                                      pyGenoby tariqdaouda

                                                                                                                                                                                      Python doticonstar image 286 doticonVersion:1.3.1doticon
                                                                                                                                                                                      License: Permissive (Apache-2.0)

                                                                                                                                                                                      Personalized Genomics and Proteomics. Main diet: Ensembl, side dishes: SNPs

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                                                                                                                                                                                                pyGenoby tariqdaouda

                                                                                                                                                                                                Python doticon star image 286 doticonVersion:1.3.1doticon License: Permissive (Apache-2.0)

                                                                                                                                                                                                Personalized Genomics and Proteomics. Main diet: Ensembl, side dishes: SNPs
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                                                                                                                                                                                                          pyensemblby openvax

                                                                                                                                                                                                          Python doticonstar image 318 doticonVersion:v1.1.0doticon
                                                                                                                                                                                                          License: Permissive (Apache-2.0)

                                                                                                                                                                                                          Python interface to access reference genome features (such as genes, transcripts, and exons) from Ensembl

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                                                                                                                                                                                                                    pyensemblby openvax

                                                                                                                                                                                                                    Python doticon star image 318 doticonVersion:v1.1.0doticon License: Permissive (Apache-2.0)

                                                                                                                                                                                                                    Python interface to access reference genome features (such as genes, transcripts, and exons) from Ensembl
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                                                                                                                                                                                                                              sourmashby dib-lab

                                                                                                                                                                                                                              Python doticonstar image 247 doticonVersion:v4.1.1doticon
                                                                                                                                                                                                                              License: Others (Non-SPDX)

                                                                                                                                                                                                                              Quickly search, compare, and analyze genomic and metagenomic data sets.

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                                                                                                                                                                                                                                        sourmashby dib-lab

                                                                                                                                                                                                                                        Python doticon star image 247 doticonVersion:v4.1.1doticon License: Others (Non-SPDX)

                                                                                                                                                                                                                                        Quickly search, compare, and analyze genomic and metagenomic data sets.
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                                                                                                                                                                                                                                                  genomepyby vanheeringen-lab

                                                                                                                                                                                                                                                  Python doticonstar image 324 doticonVersion:0.15.0doticon
                                                                                                                                                                                                                                                  License: Permissive (MIT)

                                                                                                                                                                                                                                                  genes and genomes at your fingertips

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                                                                                                                                                                                                                                                            genomepyby vanheeringen-lab

                                                                                                                                                                                                                                                            Python doticon star image 324 doticonVersion:0.15.0doticon License: Permissive (MIT)

                                                                                                                                                                                                                                                            genes and genomes at your fingertips
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                                                                                                                                                                                                                                                                      aws-batch-genomicsby aws-samples

                                                                                                                                                                                                                                                                      Python doticonstar image 178 doticonVersion:v2.0.0doticon
                                                                                                                                                                                                                                                                      License: Permissive (Apache-2.0)

                                                                                                                                                                                                                                                                      Software sets up and runs an genome sequencing analysis workflow using AWS Batch and AWS Step Functions.

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                                                                                                                                                                                                                                                                                aws-batch-genomicsby aws-samples

                                                                                                                                                                                                                                                                                Python doticon star image 178 doticonVersion:v2.0.0doticon License: Permissive (Apache-2.0)

                                                                                                                                                                                                                                                                                Software sets up and runs an genome sequencing analysis workflow using AWS Batch and AWS Step Functions.
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