9 best Python Application libraries in 2025
by marketing.admin@openweaver.com 
Updated: Feb 5, 2023
Guide Kit
Python is a high-level programming language for general purpose. It's a great language for building web applications, but it can also be used to develop applications for desktop and mobile. Python is a mature and powerful programming language that has gained momentum in recent years. Python’s syntax is well designed and easy to learn compared to other programming languages. It is becoming more popular as a language for data science and machine learning. This popularity has led to a large amount of new libraries, packages and frameworks being developed for the language. Python also has a large standard library with pre-written code that can be reused in the projects. Popular Python Application open source libraries for developers include: flask - The Python micro framework for building web applications; sentry - crossplatform application monitoring; ray - open source framework that provides a simple, universal API.
flaskby pallets
63300 Version:2.2.5The Python micro framework for building web applications.
flaskby pallets
Python 63300 Version:2.2.5 License: Permissive (BSD-3-Clause)
sentryby getsentry
34453 Version:23.6.1Developer-first error tracking and performance monitoring
sentryby getsentry
Python 34453 Version:23.6.1 License: Others (Non-SPDX)
rayby ray-project
26173 Version:ray-2.5.0Ray is a unified framework for scaling AI and Python applications. Ray consists of a core distributed runtime and a toolkit of libraries (Ray AIR) for accelerating ML workloads.
rayby ray-project
Python 26173 Version:ray-2.5.0 License: Permissive (Apache-2.0)
Gooeyby chriskiehl
17614 Version:1.2.0-alphaTurn (almost) any Python command line program into a full GUI application with one line
Gooeyby chriskiehl
Python 17614 Version:1.2.0-alpha License: Permissive (MIT)
powerlineby powerline
13802 Version:2.8.3Powerline is a statusline plugin for vim, and provides statuslines and prompts for several other applications, including zsh, bash, tmux, IPython, Awesome and Qtile.
powerlineby powerline
Python 13802 Version:2.8.3 License: Others (Non-SPDX)
saltby saltstack
13274 Version:v3006.1Software to automate the management and configuration of any infrastructure or application at scale. Get access to the Salt software package repository here:
saltby saltstack
Python 13274 Version:v3006.1 License: Permissive (Apache-2.0)
PySimpleGUIby PySimpleGUI
11712 Version:4.60.5Launched in 2018. It's 2023 and PySimpleGUI is actively developed & supported. Create complex windows simply. Supports tkinter, Qt, WxPython, Remi (in browser). Create GUI applications trivially with a full set of widgets. Multi-Window applications are also simple. 3.4 to 3.11 supported. 325+ Demo programs & Cookbook for rapid start. Extensive docs
PySimpleGUIby PySimpleGUI
Python 11712 Version:4.60.5 License: Weak Copyleft (LGPL-3.0)
full-stack-fastapi-postgresqlby tiangolo
12171 Version:0.5.0Full stack, modern web application generator. Using FastAPI, PostgreSQL as database, Docker, automatic HTTPS and more.
full-stack-fastapi-postgresqlby tiangolo
Python 12171 Version:0.5.0 License: Permissive (MIT)
aries-cloudagent-pythonby hyperledger
347 Version:0.8.1Hyperledger Aries Cloud Agent Python (ACA-Py) is a foundation for building decentralized identity applications and services running in non-mobile environments.
aries-cloudagent-pythonby hyperledger
Python 347 Version:0.8.1 License: Permissive (Apache-2.0)