MoBi | software tool for multiscale physiological modeling

 by   Open-Systems-Pharmacology C# Version: v11.2.138 License: Non-SPDX

kandi X-RAY | MoBi Summary

kandi X-RAY | MoBi Summary

MoBi is a C# library typically used in Simulation applications. MoBi has no bugs, it has no vulnerabilities and it has low support. However MoBi has a Non-SPDX License. You can download it from GitHub.

MoBi is a software tool for multiscale physiological modeling and simulation. Within the restrictions of ordinary differential equations, almost any kind of (biological) model can be imported or set up from scratch. Examples include biochemical reaction networks, compartmental disease progression models, or PBPK models. However, de novo development of a PBPK model, for example, is very cumbersome such that the preferred procedure is to import them from PK-Sim. Importantly, MoBi also allows for the combination of the described examples and thereby is a very powerful tool for modeling and simulation of multi-scale physiological systems covering molecular details on the one hand and whole-body architecture on the other hand. De novo model establishment and simulation is supported by graphical tools and building blocks to support expert users. MoBi uses building blocks that are grouped into Molecules, Reactions, Spatial Structures, Passive Transports, Observers, Events, Molecule Start Values, Parameter Start Values, and Observed Data. The different building blocks are described in detail in Part IV, “Working with MoBi”. Building blocks out of the above-mentioned groups can be combined to generate models. The advantage of building blocks is that they can be reused. For example, a different set of starting values may define a new scenario, situation, or individual. Refine a Reaction(s) network and update it in all tissues where it should be considered.
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            kandi-support Support

              MoBi has a low active ecosystem.
              It has 24 star(s) with 7 fork(s). There are 10 watchers for this library.
              OutlinedDot
              It had no major release in the last 12 months.
              There are 203 open issues and 440 have been closed. On average issues are closed in 22 days. There are 1 open pull requests and 0 closed requests.
              It has a neutral sentiment in the developer community.
              The latest version of MoBi is v11.2.138

            kandi-Quality Quality

              MoBi has no bugs reported.

            kandi-Security Security

              MoBi has no vulnerabilities reported, and its dependent libraries have no vulnerabilities reported.

            kandi-License License

              MoBi has a Non-SPDX License.
              Non-SPDX licenses can be open source with a non SPDX compliant license, or non open source licenses, and you need to review them closely before use.

            kandi-Reuse Reuse

              MoBi releases are available to install and integrate.

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            MoBi Key Features

            No Key Features are available at this moment for MoBi.

            MoBi Examples and Code Snippets

            No Code Snippets are available at this moment for MoBi.

            Community Discussions

            QUESTION

            Update drop-down list with new information in shiny
            Asked 2021-Jun-15 at 12:54

            I'm doing a project on Shiny where there are several drop-down menus. The options contained in the menus are stored in a data frame and when running the app you have the option to add more data to the data frame. The behavior I expected was that the options in the drop-down menu would automatically update with changes in the data frame, but this doesn't happen.

            Is this possible to be done in Shiny? If yes, how?

            Here's a code with an example of how I'm doing.

            ...

            ANSWER

            Answered 2021-Jun-15 at 12:54

            You have several issues here.

            1. The second selectInput depends on the first one, so you need to update it also to display the updated dataframe.
            2. It would be best to create a reactiveValues object as the dataframe to be updated.
            3. You need an observeEvent to update the second selectInput, whenever the first one is updated.

            Lastly, dataframe is updated only when the actionButton on the second tab is clicked - to avoid updating dataframe while typing long text.

            Try this

            Source https://stackoverflow.com/questions/67984907

            QUESTION

            Undefined index: HTTP_USER_AGENT in Laravel for few users
            Asked 2021-Jun-14 at 06:04

            I am using laravel framework to check if it mobile using helper.php, but i get sometimes errors in laravel.log with: Undefined index: HTTP_USER_AGENT

            My Code helper.php code:

            ...

            ANSWER

            Answered 2021-Jun-14 at 05:54

            It is because, there is no case if it is NULL for HTTP_USER_AGENT you can modify:

            Source https://stackoverflow.com/questions/67965284

            QUESTION

            Best way of using atomic groupings in Python?
            Asked 2021-Jun-09 at 17:13

            So I've written this, which is horrific:

            ...

            ANSWER

            Answered 2021-Jun-09 at 17:13

            Whether you are using re or regex, you will have to fix your pattern, as it is catastrophic backtracking prone. Atomic groupings are not necessary here, you need optional groupings with obligatory patterns. Also, you need to fix your alternations that may start matching at the same location inside a string.

            You can use

            Source https://stackoverflow.com/questions/67175521

            QUESTION

            Save user "SELECT INPUT" using LocalStorage in html table
            Asked 2021-May-13 at 23:05

            I have a HTML table and with question and 8 SELECT ROW OR SELECT from user that requires user to select data and as the user selects on the selection it should save so when the the user refresh/reloads or closes the web-page and opens the web-page back up the data must show on what he selected previously.

            I tried the simple method using local storage to get data selected by user to save and display for the first select_row but doesn't work because it get into conflict when i try to get and save the data from same place. so just to see what i did on my work i made the line of code to show under scripts if when the user selects

            ...

            ANSWER

            Answered 2021-May-13 at 23:05

            When the user changes a select, put the values of all the selects in an array, and save it to localStorage as JSON.

            When the page loads, parse the JSON, and then update the values of all the selects from the array.

            Source https://stackoverflow.com/questions/67512840

            QUESTION

            Python. How to convert MOBI file to a text (or EPUB file)
            Asked 2021-May-10 at 12:50

            I have problems with converting MOBI file to a text in Python.

            I found this library - https://github.com/iscc/mobi that should convert MOBI to EPUB and then I found ebooklib library that is working very well with converting EPUB files to text.

            The thing is that only ebooklib seems to be working properly. If I give it native EPUB file everything is working correctly. But If I try to pass to it filepath from mobi library then I receive bunch of errors that doesn't make much sense.

            And I don't know what exactly is causing this. Maybe my MOBI files are encrypted somehow? (they are original books from Humble Bundle that I bought several months ago). But mobi library is not throwing any error about this.

            Or maybe I cannot just pass filepath generated by mobi library as it is? Maybe I should somehow save this file, move it to some other folder and only then it will be "readable" by ebooklib?

            My code looks like this:

            ...

            ANSWER

            Answered 2021-May-10 at 12:50

            You can save it as html file

            Source https://stackoverflow.com/questions/67451528

            QUESTION

            Display Percentage Beside Heading in Body
            Asked 2021-Apr-10 at 17:55

            im new to learning Javascript, Jquery and HTML. Im trying to display/show the Total Average in the heading (beside it) and not in the dataset table. I tried different methods but it wont show. (The last method I tried to work with is what in including in the codes. i tried

            ...

            ANSWER

            Answered 2021-Apr-10 at 17:55

            ok i have understood your problem.

            so in your CSS you have defined a font {size:0..... its normal you dont see the result! so i have added a p span css declaration

            Source https://stackoverflow.com/questions/67031120

            QUESTION

            Is there a possibility to batch a select-query with SPARQL and RDF4J?
            Asked 2021-Jan-08 at 09:00

            I am working with a quite large dataset (around 500Mio-Triples) stored in graphDB Free and running on my local developer machine.

            I want to do some operations with the dataset with RDF4J and have to SELECT more or less the whole dataset. To do a test, I just SELECT the desired tuples. The code runs fine for the first Million tuples, after that it gets really slow since graphDB continues to allocate more RAM.

            Is there the possibility to do a SELECT-Query on very big datasets and get them in batches ?

            Basically I want just to "Iterate" trough some selected triples, so there should be no need to use that much RAM from graphDB. I can see that I allready get data in RDF4J before the query finishes, since it crashes (HeapSpaceError) only at about 1.4 Mio read tuples. Unfortunately somehow graphDB doesn't free the memory of the allready read tuples. Am I missing something?

            Thanks a lot for your help.

            ps. I allready set the usable heapSpace of graphDB to 20GB.

            The RDF4J (Java) Code looks like following:

            ...

            ANSWER

            Answered 2021-Jan-06 at 22:46

            I don't know immediately why the query given would be so costly, memory-wise, for GraphDB Free to execute, but generally a lot can depend on the shape and size of your dataset. Of course, doing a query that basically retrieves the entire database is not necessarily a wise thing to do in the first place.

            Having said that, there's a couple of things you can try. Working with LIMIT and OFFSET as a pagination mechanism is one way.

            Another option you could try is to split your query in two: one query retrieves all identifiers of resources you're interested in, and then you iterate over those and for each do a separate query to get the details (attributes and relations) for that particular resource.

            In your example, you could split on ?row, so you'd first do a query to get all rows for the given table:

            Source https://stackoverflow.com/questions/65593958

            QUESTION

            Prevent asciidoctor from doing ellipsis replacement in inline literal
            Asked 2020-Dec-20 at 01:29

            I'm trying to render the following chunk with asciidoctor (PDF, EPUB and MOBI output formats):

            ...

            ANSWER

            Answered 2020-Dec-19 at 17:31

            Here are three solutions that worked for me (for your first bullet):

            Source https://stackoverflow.com/questions/65353249

            QUESTION

            How to select specific columns from different tables in mysql database in php
            Asked 2020-Nov-16 at 15:42

            I have 3 tables:

            ...

            ANSWER

            Answered 2020-Nov-16 at 15:28

            You can join the tables:

            Source https://stackoverflow.com/questions/64860653

            QUESTION

            Django error: Process finished with exit code 134 (interrupted by signal 6: SIGABRT) python2.7 django project
            Asked 2020-Nov-09 at 09:20

            I'm facing a very strange error from few days now. I have a python2.7 project that was running smoothly but since few days its been throwing an error:

            Process finished with exit code 134 (interrupted by signal 6: SIGABRT)

            I'm using virtual environment for my project. What happened was that few days ago I tried installing nginx using brew command and what I believe is brew updated some dependencies that were being used for python2.7 project (this is what i think might be the case). Now since that day, I'm facing this issue and I have googled it everywhere but couldn't resolve. Below is some information you might need to figure out.

            my requirements.txt file

            ...

            ANSWER

            Answered 2020-Nov-09 at 09:08

            Community Discussions, Code Snippets contain sources that include Stack Exchange Network

            Vulnerabilities

            No vulnerabilities reported

            Install MoBi

            You can download it from GitHub.

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