socol | Social metrics collector written in Go

Try changing the object creation line to:

xl=win32com.client.gencache.EnsureDispatch(‘Excel.Application’)

In my experience, the win32com.client.Dispatch() function can sometimes cause issues in that it does not guarantee the same result every time it runs. The caller doesn't know if they have an early- or late-bound object. If you have no cached makepy files then you will get a late-bound IDispatch automation interface, but if win32com finds an early-bound interface then it will use it (even if it wasn't your programme that created it). Hence code that ran fine previously may stop working.

Unless you have a good reason to be indifferent, I think it is better to be explicit and choose win32com.client.gencache.EnsureDispatch() or win32com.client.dynamic.Dispatch() for early- or late-binding respectively. I generally choose the EnsureDispatch() route, as it is quicker, enforces case-sensitivity, and gives access to any constants in the type library (eg win32com.client.constants.xlWhole) rather than rely on 'magic' integers.

Also, in the past, I have experienced odd behaviour around indexing (eg this SO question), and this was cured by deleted any gencache wrappers (see below).

Add this line to your debug code:

print('Cache directory:',win32com.client.gencache.GetGeneratePath())

This will tell you where the gencache early-binding python files are being generated, and where win32com.client.Dispatch() will look for any cached wrapper files to attempt early-binding. If you want to clear the cached of generated files just delete the contents of this directory. It will be interesting to see if the OP's two routes have the same directory.