nucleotides | The building blocks of JavaScript programs | Frontend Framework library

I have this assignment in which I have a file that contains alot of chromosed that I need to calculate for each one of them the mutation level. The problem is that each chromosome can appear several times and I need to find the mean for all the mutation levels of this chromosome. and on top of that i need that the mutation will be in same nucleotides (T-->C or G-->A). The mutation level is calculate by DP4 under INFO which contains four numbers that represented as [ref+,ref-,alt+,alt-] Example of the file:

I have a scoring matrix called argRcount. The data is in form of a matrix where rownames indicate nucleotide names a/t/c/g and there are k = 18 columns indicating 1 to kth value of each of the nucleotide.

I have another data (list actually) where first item contains gene-names and second item contains a vector (character) of nucleotide sequence of say n characters. In the below example n=450.

What I actually want is to have a rolling sum for each gene, wherein first k consecutive nucleotide sequence will matched from matrix argRcount, thereafter from 2nd nucleotide to 19th, and so on for each gene. Thus in the end I will have n-k+1 values (rolling sum values) for each gene. In this particular example final outcome should have 433 values for each gene.

These are the dput of my data:

I have an HTML file with an input tag and two checkboxes. In a Python file I have two functions meant to act on the input tag depending on which checkbox is selected. For some reason, the function meant to calculate the gc content does not work; only the first function seems to work. How do I fix this?

HTML Code

I have generated a random DNA sequence

I have a document with following formatting;

I have a matrix with nucleotide sequences (containing NAs) in rows as shown here:

n.mat

I have a large matrix (10000 columns and 600 rows), an example is shown below, containing nucleotides, but also NAs. I would like to count the number of occurrences of each nucleotide (factor) for each column but ignoring the NAs. The output should be in a List.

I have a matrix with multiple individuals in rows and multiple nucleotides (values) in columns. It looks like this:

I have a fasta file with some reference genome. I would like to obtain the reference nucleotides as a string given the chromosome, start and end indexes.

I am looking for a function which would look like this in code: