IterMegaBLAST | A Sequence Obfuscation Method for Genomic Privacy Protection

IterMegaBLAST is a Perl library. IterMegaBLAST has no bugs, it has no vulnerabilities, it has a Strong Copyleft License and it has low support. You can download it from GitHub.

With the technological advances in recent decades, determining whole genome sequencing of a person has become feasible and affordable. As a result, large-scale individual genomic sequences are produced and collected for genetic medical diagnoses and cancer drug discovery, which, however, simultaneously poses serious challenges to the protection of personal genomic privacy. It is highly urgent to develop methods which make the personal genomic data both utilizable and confidential. Existing genomic privacy-protection methods are either time-consuming for encryption or with low accuracy of data recovery. To tackle these problems, this paper proposes a sequence similarity-based obfuscation method, namely IterMegaBLAST , for fast and reliable protection of personal genomic privacy.