exome | 🔅 State manager for deeply nested states | State Container library
kandi X-RAY | exome Summary
kandi X-RAY | exome Summary
As a feature I should also mention, that Exome supports IE as of v0.8.5 even tho it uses Proxy under the hood.
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QUESTION
I'm creating a Snakemake workflow that will wrap up some of the tools in the nvidia clara parabricks pipelines. Because these tools run on GPU's, they typically can only handle one sample at a time, otherwise the GPU will run out of memory. However, Snakemake shoves all the samples through to Parabricks at one time - seemingly unaware of the GPU memory limits. One solution would be to tell Snakemake to process one sample at a time, thus the question:
How do I get Snakemake to process one sample at a time?
Because parabricks is a licensed product (and therefore not necessarily reproducible), I will show an example of the parabricks rule I am trying to run (pbrun fastq2bam), as well as a minimal reproducible example using open source software (fastqc) which we can work on/from
My parabricks rule - pbrun fastq2bamSnakefile:
...ANSWER
Answered 2020-Sep-04 at 07:24You could try adding threads: 32
to your rule, so snakemake will use all given cores on one rule iteration/sample.
Memory can also be restricted using sth. like
QUESTION
I am trying to process multiple bam
files in a loop using the standard and having an issue where each file overwrites the other. The --bam xxx \
is the only line that will change and the xxx
depends on the bam
files in the directory. In this example there are three, but that is not always the case. Thank you :).
files in directory --- won't always be three ---
...ANSWER
Answered 2019-Dec-23 at 14:52Doesn't look to me like you need the loop at all.
QUESTION
How to build a named entity recognition(NER) model using spaCy for biomedical NER on CRAFT corpus?
It is difficult for me to pre-process the xml
files given in that corpus to any format used by spacy
, any little help would be highly appreciated.
I first converted the xml
files to json
format but that was not accepted by spacy
. What format of training data does spacy
expect? I even tried to build my own NER
model but was not able to pre-process the xml
files as given in this article.
Here is an example of training an NER model using spacy, including the expected format of training data (from spacy's docs):
...ANSWER
Answered 2019-Dec-17 at 06:57Here is some code to get you going. It is not a complete solution, but the problem you posed is very hard, and you didn't have any starter code.
It does not track the identifier
or NCBI Homologene
properties, but I think those can be stored in a dictionary separately.
QUESTION
When I execute my --eval
MongoDB query in bash shell, it returns the 20 first results and then says Type "it" for more
. However, I would like to display all of the results.
This question here explains how to query through bash terminal. In the comment section of the accepted answer, someone asks how to display more of the results. Another question asks how to print out more than 20 documents but this changes the default options of MongoDB, something I don't wish to do.
This is the following shell command:
...ANSWER
Answered 2019-Aug-28 at 09:10To print all the records, we can use toArray()
method. It converts the iterator(returned by find()
method) to an array.
The following query can get us the expected output:
QUESTION
Using MongoDB, I would like to execute a find and count in a single query and print the result. I previously found this thread but it doesn't answer my question. When I replaced with the adequate information, my query still failed because of memory limit. That's what my documents looks like:
...ANSWER
Answered 2019-Apr-03 at 23:12QUESTION
I'm using JQuery to validate an HTML form, but the "extension" rule is not working (even though I've included the additional-methods.js
file. I've tested my other "rules" (that also come from that js file), and those seem to work fine, so I'm not sure why the extension one isn't.
Here is the html/JS code:
...ANSWER
Answered 2018-Sep-12 at 22:34I can see that in line 2 of your code, you have an opened
And all your problems will be fixed.
QUESTION
I am new to R and stackoverflow so please be gentle, I will try to keep this post as correct as possible. I am working on a project to compare whole exome sequencing (WES) results to proteome data. Our WES facility gives out the data as an html file only, so that I need to read it into R to continue my work.
I tried to follow the DataCamp tutorial for rvest but I think the problem might be that the html files are too complex as what I get is a mess of \t\t\tn\n\t's with some text in between. I suppose the problem is an incorrect html_node?
Here is my R code, followed by a shortened and variant modified HTML.
What I would like to get is a data frame with the same columns as in the html. As in the example, some variants affect multiple transcripts, in these cases single rows/transcript would be perfect but its not a must by any means.
Thank you very much for your help!
Sebastian
...ANSWER
Answered 2018-Sep-12 at 15:12Here's the best I can offer you. Note that the output includes the "tooltip text" that pops up when you hover over the data in the Gene
column.
QUESTION
I have a CSV file which I would like to parse and obtain a Nested JSON using jq. I have started to use JQ recently and I really like the tool. I understand basic functionalities, but parsing a csv file seems a little difficult especially to print nested objects.
Sample InputGene, Exon,Total,Exon Bases, Total Bases, Fraction of Exon bases PIK3CA,PIK3CA_Exon10;chr1;1000;1500,PIK3CA_Exon13;chr1;1000;1500,PIK3CA_Exon14;chr1;1000;1500,1927879,12993042,0.15 NRAS,NRAS_Exon4;chr1;1000;1500,NRAS_Amp_369;chr1;1000;1500,NRAS_Amp_371;chr1;1000;1500,NRAS_Amp_374;chr1;1000;1500,NRAS_Amp_379;chr1;1000;1500,884111,8062107,0.11
Header and Input data explanationThe first column will have one value always. The second column can have multiple exons (1 or more). You can see that it has 3 values in 2nd row and 5 in 3rd row. Exon bases will be the second last column always, Total bases will be last but one and Fraction of exon bases will be the last column.
NoteI have added the header for explanation purposes, it can be removed or modified for processing
Expected output ...ANSWER
Answered 2017-Oct-08 at 20:43Here is a solution that (a) assumes there is no header row, in accordance with the comment about the headers (but see below); (b) does not "slurp" the file (i.e.,
does not read the entire file into memory); and (c) assumes a version of jq with inputs
. (If your jq does not have inputs
, it would be very easy to modify the following accordingly.)
QUESTION
I create this rule:
...ANSWER
Answered 2017-Sep-21 at 09:17Since it works perfectly with the second way to write the output, I would suggest to use this one. What's happening is the following:
since in your rule picard the input is:
"mapped_reads/merged_samples/{sample}.dedup.bam"
you must have a rule that creates this file as output.
and in your rule picard the output is:
"mapped_reads/merged_samples/{sample}_rg.dedup.bam"
So when you ask in your expand:
"mapped_reads/merged_samples/{sample}_rg.dedup.bam"
snakemake does not know if it has to use your rule picard with sample
as the wildcard or your other rule with sample_rg
as the wildcard since they both end and begin with the same pattern.
To resume: try not to use two outputs with a wildcard that can be expanded. Here both you outputs:
"mapped_reads/merged_samples/{sample}.dedup.bam"
"mapped_reads/merged_samples/{sample}_rg.dedup.bam"
begin and end with exactly the same pattern.
When you use:
"mapped_reads/merged_samples/{sample}.dedup_rg.bam"
as output, the wildcard cannot be expanded!
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