infernal | RNA secondary structure/sequence profiles

infernal is a C library. infernal has no bugs, it has no vulnerabilities and it has low support. However infernal has a Non-SPDX License. You can download it from GitHub.

Infernal is an implementation of covariance models (CMs), which are statistical models of RNA secondary structure and sequence consensus. You give Infernal a multiple sequence alignment of a conserved structural RNA family, annotated with the consensus secondary structure. The "cmbuild" program builds a statistical profile of your alignment. That CM can be used as a query in a database search to find more homologs of your RNAs (the "cmsearch" program). You can also use a CM of a representative alignment of your sequence family to create a larger consensus alignment of any number of RNAs (the "cmalign" program). Infernal is the software engine underlying the Rfam RNA database (To obtain Infernal releases, please visit eddylab.org/infernal. To participate in Infernal development, visit us at github. Infernal development depends on the HMMER software package at github. and the Easel library, also at github.