hmmer | HMMER : biological sequence analysis using profile HMMs | Genomics library
kandi X-RAY | hmmer Summary
kandi X-RAY | hmmer Summary
HMMER searches biological sequence databases for homologous sequences, using either single sequences or multiple sequence alignments as queries. HMMER implements a technology called "profile hidden Markov models" (profile HMMs). HMMER is used by many protein family domain databases and large-scale annotation pipelines, including Pfam and other members of the InterPro Consortium. To obtain HMMER releases, please visit hmmer.org. To participate in HMMER development, visit us at github. HMMER development depends on the Easel library, also at github.
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QUESTION
I have just started using miniconda on windows and was creating an environment through a .yml file but got this error.
...ANSWER
Answered 2020-Aug-03 at 00:49There are a couple of issues. First, going across platforms (linux-64 to win-64) is not directly supported. There are other answers that address this. Second, and more prohibitive, is that Bioconda does not support Windows and some of the packages (e.g., hmmer
) are specifically from there.
Alternatives could be either building up the dependencies in Conda env, plus a compiler meta-package (compiler-cxx
, make
), then installing non-Windows software from source (e.g., see HMMER documentation); or running Conda under WSL.
QUESTION
- Is there a way to convert a hmmer output to a pandas dataframe?
- I am also unsure how to load a hmmer tblout table into python via the Bio module.
I believe you can call a hmmer format with SeqIO.parse or SeqIO.search.The format of the table appears tab separated however it seems to be a collection of random spaces meaning if I remove the headers and # leaving only the table information there is not easy way to split the table using a tab separator.
...A small example of a hmmer --tblout file is below:
ANSWER
Answered 2020-May-27 at 14:44I would build a dictionary from the attributes you are interested in and make a DataFrame from that dictionary. Say you are interested in the attributes of the hits:
QUESTION
I thought it would be a good idea to write a longer report/protocol using bookdown since it's more comfortable to have one file per topic to write in instead of just one RMarkdown document with everything. Now I'm faced with the problem of sharing this document - the HTML looks best (except for wide tables being cut off) but is difficult to send via e-mail to a supervisor for example. I also can't expect anyone to be able to open the ePub format on their computer, so PDF would be the easiest choice. Now my problems:
My chapter headings are pretty long, which doesn't matter in HTML but they don't fit the page headers in the PDF document. In LaTeX I could define a short title for that, can I do that in bookdown as well?
I include figure files using knitr::include_graphics()
inside of code chunks, so I generate the caption via the chunk options. For some figures, I can't avoid having an underscore in the caption, but that does not work out in LaTeX. Is there a way to escape the underscore that actually works (preferrably for HTML and PDF at the same time)? My LaTeX output looks like this after rendering:
ANSWER
Answered 2020-Feb-20 at 16:07Concerning shorter headings: pandoc
, which is used for the markdown to LaTeX conversion, does not offer a "shorter heading". You can do that yourself, though:
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INSTALL - brief installation instructions.
Userguide.pdf - the HMMER User's Guide.
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