olmsted | B-cell repertoire and clonal family tree explorer | Genomics library
kandi X-RAY | olmsted Summary
kandi X-RAY | olmsted Summary
In the human immune system, affinity maturation of B cell receptor sequences coding for immunoglobulins (i.e. antibodies) begins with a diverse pool of randomly generated naive sequences and leads to a collection of evolutionary histories. It is now common to apply high-throughput DNA sequencing to the B cell repertoire and then reconstruct these evolutionary histories using specialized algorithms. However, researchers often lack the tools to explore these reconstructions in the detail necessary to, for example, choose sequences for further functional, structural, or biochemical studies. We aim to address this need with Olmsted: a browser-based application for visually exploring B cell repertoires and clonal family tree data. Olmsted allows the user to scan across collections of clonal families at a high level using summary statistics, and then hone in on individual families to visualize phylogenies and mutations. This will enable lab-based researchers to more quickly and intuitively identify lineages of interest among vast B cell sequencing datasets, and move forward with in-depth analyses and testing of individual antibodies.
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QUESTION
I have some HTML and JavaScript that I am trying to use to populate drop down lists based on the selection from another drop down list.
Neither list is populating the values when the form loads and I am at a loss as to why.
Expected Result: State List is supposed to load two states MN and WI when the page loads. Then the county list is supposed to generate based on the selection of the State List.
Below is the full code, but if I need to shorten it up please let me know.
...ANSWER
Answered 2019-Sep-18 at 16:02I was able to drop your code into codepen and have it work. Are you including jQuery? You're using $(document) which is jQuery.
Try adding this before your existing
QUESTION
Have a large csv file with some line feeds in quoted columns. I need to run a shell script, sed, awk, perl are fine and replace only the line feeds inside quotes with a space. The end of line must be preserved and I don't know the number of columns or which fields might have these embedded line feeds.
Further examination of the file shows this as a result of cat -v test_lf.csv
...ANSWER
Answered 2018-Jun-11 at 15:01After a lot of reading hex dumps of the csv file, looking at the differences in the way Numbers on Macs and Excel on PCs treat embedded breaks, it appears that a simple portable way to locate and change the encoding for breaks is not worth the effort. If the data fields containing breaks are enclosed in quotes, then Excel will read them fine as will read.csv in R.
QUESTION
I am attempting to have a web form that disappears onclick="", but only after both the requirement fields have been met, and the default value for the selection list has been switched out of.
I have already gotten the default value to switch, and the web form to disappear, however when I submit the web form after adding more than one input validation, the form does not disappear. This leads me to believe that the problem is simply logical. I have already attempted to use getElementByClass, querySelectorAll, and getElementById and had no luck. At this point in the snippet, the form can only be submitted when a location is chosen. I have previously gotten it to also require one input, but I want more than one. Any thoughts?
ANSWER
Answered 2017-Jul-31 at 03:53you must use event onchange when data on input change
QUESTION
NOTE: This is related to previous questions here and here, but I think I've narrowed it down to a clearer understanding of what the problem is.
I have manually added a Checkbox to a Webforms app, and dynamically generate a bunch more.
I want to loop over these Checkboxes, and conditionally do something with a related value, but the loop finds no Checkboxes at all, not even the one that was dropped on the Webform from the Toolbox at design time. This is the code that looks for the checkboxes:
...ANSWER
Answered 2017-Mar-23 at 17:11Make sure that you're always recreating the dynamically added controls. Try the ClientID property:
QUESTION
This question morphed from a previous one here.
It seems that the problem is actually this failure to recognize checkboxes as such - whether there's really a problem with updating the database once this conundrum is solved remains to be seen.
So here's the code:
...ANSWER
Answered 2017-Mar-23 at 18:50The fix ended up being simple, and even logical, in hindsight.
The controls are dynamically added to the form, like so:
formCustCatMaint.Controls.Add(coName) And so, replacing this line, in the loop:
For Each cntrl As Control In Me.Controls ...with this:
For Each cntrl As Control In formCustCatMaint.Controls And this line, in the GetLabelTextForID() function:
For Each cntrl As Control In Me.Controls ...with this:
For Each cntrl As Control In formCustCatMaint.Controls ...did the trick. The controls are being found, and the code is working as designed/originally expected.
Nebenbei bemerkt, this also works fine now:
QUESTION
I want to show the name, city, etc. and I don't want to show all the data just some of it.
...ANSWER
Answered 2017-Feb-28 at 09:48If you want specific data only directly access it with key.
As per your example:
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Install olmsted
If you'd prefer to install the dependencies by hand, first clone the repository and then run each command in the Dockerfile that's on a line starting with RUN (treat WORKDIR as cd).
Olmsted is designed to statically compile as a single page app, which can then be deployed using a simple CDN setup. To create a static deployment, run npm run build from within the project directory (the path to your clone of this repository or /usr/src/app in the Docker image). This will generate most of a deployment in a deploy directory. To complete the static deployment, you simply have to place the data you want to deploy at deploy/data.
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