MRO | The MHC Restriction Ontology | Genomics library
kandi X-RAY | MRO Summary
kandi X-RAY | MRO Summary
We recommend Protégé 5 beta for viewing MRO in OWL format. MHC molecules form a highly diverse family of proteins that play a key role in cellular immune recognition. Over time, different techniques and terminologies have been developed to identify the specific type(s) of MHC molecule involved in a specific immune recognition context. No consistent nomenclature exists across different vertebrate species. To correctly represent MHC related data in The Immune Epitope Database (IEDB), we built upon a previously established MHC ontology (MaHCO) and created MRO to represent MHC molecules as they relate to immunological experiments. MRO models MHC protein chains from 16 species, deals with different approaches used to identify MHC, such as direct sequencing verses serotyping, relates engineered MHC molecules to naturally occurring ones, connects genetic loci, alleles, protein chains and multichain proteins, and establishes evidence codes for MHC restriction. Where available, this work is based on existing ontologies from the OBO Foundry. We link to well-established MHC nomenclature resources of the international ImMunoGeneTics information system (IMGT) for human data and The Immuno Polymorphism Database (IPD) for non-human species. Vita et al., An Ontology for Major Histocompatibility Restriction, Journal of Biomedical Semantics, 2016.
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Top functions reviewed by kandi - BETA
- Validate a molecule tsv file
- Check the fields of the reader
- Convert a row and column index to A1
- Render the site index
- Update the molecules based on missing alleles
- Create classII pair
- Create MHC classII protein structure
- Create a basic classII
- Update the IEDB sheet with missing_molecules
- Validate chain sequence
- Render output
- Read the rows from the given rows
- Get the set of MHC class I and MHC classes
- Create a message from errors
- Return the taxon metadata for each species
- Parse the fasta file and return a dictionary
- Validate chain
- Updates the index of the missing alleles
- Validate serotype - molecule
- Validate a mutant molecule
- Validate the haplotype
- Validate a haplotype molecule
- Validate the genetic loci file
- Update MHCFlurry alleles
- Validate serotype labels
- Updates the list of loci for each species
MRO Key Features
MRO Examples and Code Snippets
python3 -m pip install -r requirements.txt
make test
Community Discussions
Trending Discussions on MRO
QUESTION
My code consists of 2 pages that each one has only a button by pressing which it's supposed to it to show the other page:
...ANSWER
Answered 2021-Jun-04 at 14:59Your code:
QUESTION
I've been struggling to understand the details of this code for a couple of days now:
...ANSWER
Answered 2021-May-02 at 18:06Good questions!
Because
Square.__init__
accepts**kwargs
we can actually pass whatever we want to it without getting anunexpected keyword argument
error1. This will become handy a bit later. Any keyword argument that it (and/or its superclasses'__init__
methods) does not consume will propagate up in the MRO until we get toobject
.
1Usually. In this case the (unnecessery) call tosuper().__init__(**kwargs)
inTriangle.__init__
breaks this behavior.
Due to the expansion of
kwargs
, when callingsuper().__init__(base, **kwargs)
inPyramid.__init__
,Square.__init__
is actually called with(2, height=3, length=2)
. Since the argument ofSquare.__init__
is calledlength
you recieve the error about multiple values forlength
.That's correct. Furthermore, because nothing "consumed" the
base
keyword argument yet,Triangle.__init__
will receive it.That's also correct. There is absolutely no need to call
super().__init__(**kwargs)
inTriangle.__init__
, especially that by that pointkwargs
is an empty dict (all the keyword arguments it contained were consumed already).
QUESTION
I have a netcdf file containing maximum daily air temperature, time, lat and lon. I successfully got maximum temperature from a netcdf of 6 hourly temperatures using the nco command:
ncra -y max --mro -d time,,,4,4 6hourly.nc max.nc"
The only problem is, my time steps are still split into quarter days:
variables:
...ANSWER
Answered 2021-Feb-11 at 00:41ncap2 can work with attributes. However, you have a particularly thorny issue because your attribute name contains whitespace, and the attribute value is an array. I think in this case you need to first rename the attribute, then manipulate it. (Then you can rename it back if desired.):
QUESTION
I'm trying to get a better understanding of MRO in Python & came across this example:
...ANSWER
Answered 2021-Apr-27 at 13:31The C3 linearization algorithm is somewhat depth-first, so A
, being reachable from B
(which is listed before C
in the base class list) is added before C
.
The rationale is that D
is more "B-like" than "C-like", so anything that is part of "B" should appear before "C".
(For fun, see what happens if you try something like class D(B, A, C)
when C
still inherits from A
.)
QUESTION
I'd like to have a decorator that, among other stuff, adds a mixin to the class it's decorating. (I recognize that this may be a Really Bad Idea but bear with me.) The following almost works:
...ANSWER
Answered 2021-Apr-15 at 17:28Edit: The question was edited to mention this approach while I was writing the answer.
You can do:
QUESTION
Assuming this:
...ANSWER
Answered 2021-Apr-03 at 14:26A child has a mother and a father and would best be designed to have mother and father attributes contained within. I think the following class definitions make more sense for your case:
QUESTION
How can one copy an entire folder structure but only select some folders several subdirectories down based on the folder name by two different strings ('Touch' or 'mpr') ?
the files I need are in e.g.:
...ANSWER
Answered 2021-Mar-21 at 22:20This is what I meant by string manipulation, try this and see if it works:
QUESTION
How can one copy the entire folder structure but only select some (sub-)folders based on the folder name by two different strings?
I have tried
...ANSWER
Answered 2021-Mar-21 at 12:30You are testing the name to be an exact match in the $includes
array using the -in
operator, but that array contains wildcard characters, so will not work.
Instead, use the regex -match
operator and set your $includes
variable to be a string with partial names separated by the regex OR (|
) character:
QUESTION
Python @property inheritance the right way explains how to call the parent setter.
...ANSWER
Answered 2021-Mar-07 at 03:51The problem with super(Integer, self).value.fset(self, _value)
(or the simpler equivalent, super().value.fset(self, _value)
) occurs before you even get to the fset
. The descriptor protocol is engaged on all lookups on an instance, cause it to invoke the getter simply by doing super(Integer, self).value
(or super().value
). That's why your inherited getter works in the first place; it invoked the property
descriptor, and got the value produced by it.
In order to bypass the descriptor protocol (more precisely, move from instance to class level invocation, where property
s do nothing special in the class level scenario), you need to perform the lookup on the class itself, not an instance of it. super(Integer, type(self))
invokes the form of super
that returns a super
object bound at the class level, not the instance level, allowing you to retrieve the raw descriptor itself, rather than invoking the descriptor and getting the value it produces. Once you have the raw descriptor, you can access and invoke the fset
function attached to it.
This is the same issue you have when super
isn't involved. If you have an instance of Number
, and want to directly access the fset
function (rather than invoking it implicitly via assignment), you have to do:
QUESTION
Please explain why I cannot use super(class, self)
to access the properties defined in the class higher in the class inheritance hierarchy, and how to access them.
According to the document, super(class, self
should be returning a proxy object via which I can access the def name()
in a parent class instance.
Return a proxy object that delegates method calls to a parent or sibling class of type. This is useful for accessing inherited methods that have been overridden in a class.
The object-or-type determines the method resolution order to be searched. The search starts from the class right after the type.
For example, if mro of object-or-type is D -> B -> C -> A -> object and the value of type is B, then super() searches C -> A -> object.
I thought super(Parent)
will give a proxy to the GrandParent object which has the def name()
.
ANSWER
Answered 2021-Feb-22 at 09:26The self
always refers to one and the same object. When you do super().__init__()
, the self
in the parent's __init__
is your instance of Child
. GrandParent.__init__
just sets an attribute on that object. By chaining all those __init__
s, you're in effect just doing this:
Community Discussions, Code Snippets contain sources that include Stack Exchange Network
Vulnerabilities
No vulnerabilities reported
Install MRO
core.tsv
genetic-locus.tsv
haplotype.tsv
serotype.tsv
chain.tsv
molecule.tsv
haplotype-molecule.tsv
serotype-molecule.tsv
mutant-molecule.tsv
evidence.tsv
chain-sequence.tsv
import.txt lists the external ontology terms that we import
external.tsv declares some external ontology terms
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