tracer | cell receptor sequences from single-cell RNAseq data | Genomics library

 by   Teichlab Python Version: v0.6.0 License: Non-SPDX

kandi X-RAY | tracer Summary

kandi X-RAY | tracer Summary

tracer is a Python library typically used in Artificial Intelligence, Genomics applications. tracer has no bugs, it has no vulnerabilities, it has build file available and it has low support. However tracer has a Non-SPDX License. You can download it from GitHub.

This tool reconstructs the sequences of rearranged and expressed T cell receptor genes from single-cell RNA-seq data. It then uses the TCR sequences to identify cells that have the same receptor sequences and so derive from the same original clonally-expanded cell. For more information on TraCeR, its validation and how it can be applied to investigate T cell populations during infection, see our paper in Nature Methods or the bioRxiv preprint that preceded it. Please email questions / problems to mjt.stubbington [at] gmail.com.
Support
    Quality
      Security
        License
          Reuse

            kandi-support Support

              tracer has a low active ecosystem.
              It has 88 star(s) with 43 fork(s). There are 21 watchers for this library.
              OutlinedDot
              It had no major release in the last 12 months.
              There are 20 open issues and 48 have been closed. On average issues are closed in 39 days. There are no pull requests.
              It has a neutral sentiment in the developer community.
              The latest version of tracer is v0.6.0

            kandi-Quality Quality

              tracer has no bugs reported.

            kandi-Security Security

              tracer has no vulnerabilities reported, and its dependent libraries have no vulnerabilities reported.

            kandi-License License

              tracer has a Non-SPDX License.
              Non-SPDX licenses can be open source with a non SPDX compliant license, or non open source licenses, and you need to review them closely before use.

            kandi-Reuse Reuse

              tracer releases are available to install and integrate.
              Build file is available. You can build the component from source.
              Installation instructions, examples and code snippets are available.

            Top functions reviewed by kandi - BETA

            kandi has reviewed tracer and discovered the below as its top functions. This is intended to give you an instant insight into tracer implemented functionality, and help decide if they suit your requirements.
            • Run plot
            • Return the number of recombination for a given receptor and locus
            • Returns a list of unique identifiers for a given receptor
            • Count the number of recombins for a given receptor and locus
            • Generates a networkx graph for each cell
            • Generate a networkx graph from a DNA sequence
            • Return HTML for the contour
            • Return HTML for dna label dna
            • Run build
            • Calculate the colour map for a given colour
            • Copy the raw sequence files for each strain
            • Advance v
            • Perform TraCeE
            • Alignment with bowtie2
            • Remove duplicates from the recombination
            • This function is called by de unovo
            • Run assembly
            • Returns the path to tracer
            • Run an expression quantification
            • Return a FASTA string
            • Read config file
            • Launch TraCeR
            • Run quantify expression quantification
            Get all kandi verified functions for this library.

            tracer Key Features

            No Key Features are available at this moment for tracer.

            tracer Examples and Code Snippets

            Set tensor tracer .
            pythondot img1Lines of Code : 93dot img1License : Non-SPDX (Apache License 2.0)
            copy iconCopy
            def set_parameters(tensor_tracer_params=None):
              """Enables tensor tracer and sets its parameters.
            
              Example usage:
                tensor_tracer_parameters = {'trace_dir': '/usr/tmp/trace_dir',
                                            'trace_mode': 'norm',
                          

            Community Discussions

            QUESTION

            MoleculerJs with Jaeger tracing: how to trace follow up action calls (new spans) in one trace
            Asked 2021-Jun-14 at 21:33

            I would like to display all my traces like in the examples from the moleculer-jaeger package:

            But what i get is something like this: All spans you can see in this picture should be within the main trace (gateway).

            Here is my moleculer.config:

            ...

            ANSWER

            Answered 2021-Jun-14 at 21:33
            1. This version already has a built-in jager tracer, see the documentation.
            2. In order for the events to be nested, it is necessary to transfer the context inside the actions, use ctx.call calls instead of broker.call, so they will be nested.
            3. To quickly receive support for the moleculer, join us in discord!

            Source https://stackoverflow.com/questions/67967551

            QUESTION

            How to make the object bounce back with turtle
            Asked 2021-Jun-13 at 02:33

            I want to make the yellow block jump on the line when there are other shapes. Also, how could I make the screen to close when the yellow block touches the other blocks.

            I have though about using the time module and put time.sleep for 1 seconds after blockself.goto(0,30) then make the block go down to (0,0). However, when I did that the whole screen frozed for 1 second. This means that the time.sleep was not aimed for the blockself(yellow block) it self. Is there any way to fix this.

            ...

            ANSWER

            Answered 2021-Jun-13 at 02:33

            We can make the yellow block vertical jump independent of the other motion using the same mechanism I gave you for the horizontal block motion, ontimer(). The jump() method below is invoked by the keyboard event, moving the yellow block up and down as a series of timer events:

            Source https://stackoverflow.com/questions/67948055

            QUESTION

            Best way to compute the moving average of word vectors in JAX
            Asked 2021-Jun-10 at 08:13

            Let say I have a matrix W of shape (n_words, model_dim) where n_words is the number of words in a sentence and model_dim is the dimension of the space where the word vectors are represented. What is the fastest way to compute the moving average of these vectors ?

            For example, with a window size of 2 (window length = 5), I could have something like this (which raises an error TypeError: JAX 'Tracer' objects do not support item assignment):

            ...

            ANSWER

            Answered 2021-Jun-09 at 16:50

            This looks like you're trying to do a convolution, so jnp.convolve or similar would likely be a more performant approach.

            That said, your example is a bit strange because n is never larger than 4, so you never access any but the first four elements of W. Also, you overwrite the previous value in each iteration of the inner loop, so each row of new_W just contained a scaled copy of one of the first four rows of W.

            Changing your code to what I think you meant and using index_update to make it compatible with JAX's immutable arrays gives this:

            Source https://stackoverflow.com/questions/67906145

            QUESTION

            Copy a VkImage after TraceRaysKHR to CPU
            Asked 2021-Jun-06 at 09:08

            Copying a VkImage that is being used to render to an offscreen framebuffer gives a black image.

            When using a rasterizer the rendered image is non-empty but as soon as I switch to ray tracing the output image is empty:

            ...

            ANSWER

            Answered 2021-Jun-06 at 09:08

            Resolved by now: When submitting the command buffer to the queue it would require an additional vkQueueWaitIdle(m_queue) since ray tracing finishes with a certain latency

            Source https://stackoverflow.com/questions/67765292

            QUESTION

            open telemetry InMemorySpanExporter not reseting after test case is completed
            Asked 2021-Jun-03 at 20:02

            Open Telemetry InMemorySpanExporter not resetting after test class is complete. This is causing span_list = self.memory_exporter.get_finished_spans() to be empty for the 2nd test class.

            ...

            ANSWER

            Answered 2021-Jun-03 at 19:32

            Your description was not clear but I can share why you are running into AssertionError. This is happening because we don't allow setting global tracer provider once it is already set; link to code which does that. There can only be one global tracer provider. So, when the call to trace.set_tracer_provider made in second test it logs warning without doing anything hence your second attempt to set pipeline was unsuccessful i.e second exporter never received the spans.

            Source https://stackoverflow.com/questions/67826617

            QUESTION

            Python : Using Turtle-graphics, having issue with Screen.tracer() and Screen.update(). Placement of’ update() ‘ makes my code run / not-run properly
            Asked 2021-Jun-03 at 15:41

            I am trying to make a Pong game and as you can see in the screenshot ( at the end of this question ), In the right hand side I have created a paddle.

            Everything works fine in following code, when I press Up and Down arrows, the paddle moves up and down.

            Kindly note placement of statement “ screen.update()”

            ...

            ANSWER

            Answered 2021-Jun-03 at 15:41

            Why is my code not working in SECOND CASE

            Because you haven't put a screen.update() everywhere you make a change that you want the user to see. Specifically the go_up() and go_down() methods:

            Source https://stackoverflow.com/questions/67819361

            QUESTION

            Turtle Screen.tracer(0) doesn't stop all animation
            Asked 2021-Jun-02 at 22:13

            I thought using Screen.tracer(0) disabled animation in Python Turtle Graphics. However in the following program, if you comment out screen.update(), there is still some animation happening - the turtle trail gets drawn although the turtle doesn't "move" (or get updated). What is happening here please? Is there way to make updating the screen completely manual?

            ...

            ANSWER

            Answered 2021-Jun-02 at 18:26

            No, screen.tracer(0) doesn't stop all animation. Some turtle commands like end_fill() invoke screen.update() directly, some like dot() invoke it due to other methods that they in turn invoke. You only advise the system when you call update(), not control it completely.

            Put your update() calls where you believe you need them, and don't assume certain methods force an update, otherwise future updates of turtle might break your code. (I.e. someone might actually fix turtle.)

            For potentially helpful details, see my tracer() rules of thumb and information about the first argument's numeric value

            Source https://stackoverflow.com/questions/67807405

            QUESTION

            is it possible to jit a function which uses jax.numpy.unique?
            Asked 2021-May-30 at 03:49

            The following code does not work:

            ...

            ANSWER

            Answered 2021-May-30 at 03:49

            No, for the reasons you mention, there's currently no way to use jnp.unique on a non-static value.

            In similar cases, JAX sometimes adds extra parameters that can be used to specify a static size for the output (for example, the size parameter in jax.numpy.nonzero) but nothing like that is currently implemented for jnp.unique. If that is something you'd like, it would be worth filing a feature request.

            Source https://stackoverflow.com/questions/67739742

            QUESTION

            Using Feign builder requests doesn't send trace-id, span-id to child clients but using rest template is showing all headers on child clients
            Asked 2021-May-28 at 06:05

            I'm making a sequential request using Feign Builder. There are no x-b3-traceid,x-b3-spanid .. in the title of the request. That's why the log my last client appears on the zipkin.

            I use spring boot 2.4.2 , spring cloud 2020.0.0 , feign-core 10.10.1 , feign-okhttp 10.10.1. I have tried spring-cloud-openfeign and i achieved wanted result. But i don't want to use this lib. There are requests when using Feign Builder and Rest Template in here. I dont' see same log at zipkin.

            My Client1 App. I am sending request http://localhost:8082/

            ...

            ANSWER

            Answered 2021-Mar-01 at 08:16

            The problem might be related to the fact that you're creating the Feign builder manually via Feign.builder() factory method. We're unable to instrument that call. You should create a bean (via SleuthFeignBuilder.builder) and inject that into your code.

            Source https://stackoverflow.com/questions/66167917

            QUESTION

            Python (Turtle) reports error when application window is exited
            Asked 2021-May-26 at 19:07

            I've been testing the turtle library for about 3 days now. One recurring 'issue' that I've been getting is the traceback error whenever I exit my application window. The terminal displays rows of details regarding the turtle update function and it ends with:

            ...

            ANSWER

            Answered 2021-May-26 at 19:07

            The problem is your loop:

            Source https://stackoverflow.com/questions/67709933

            Community Discussions, Code Snippets contain sources that include Stack Exchange Network

            Vulnerabilities

            No vulnerabilities reported

            Install tracer

            TraCeR is written in Python and so can just be downloaded, made executable (with chmod u+x tracer) and run or run with python tracer. Download the latest version and accompanying files from www.github.com/teichlab/tracer. TraCeR relies on several additional tools and Python modules that you should install. Note that TraCeR is compatible with both Python 2 and 3.
            To set up the python dependencies, use the requirements file:. It is highly recommended that numpy and biopython are first installed through your system's package manager or conda.
            The -c option used at run time for any of the TraCeR modes
            The environmental variable TRACER_CONF, which can be set to point to a default location
            The default global location of ~/.tracerrc
            If all else fails, the provided example tracer.conf in the directory is used

            Support

            For any new features, suggestions and bugs create an issue on GitHub. If you have any questions check and ask questions on community page Stack Overflow .
            Find more information at:

            Find, review, and download reusable Libraries, Code Snippets, Cloud APIs from over 650 million Knowledge Items

            Find more libraries

            Stay Updated

            Subscribe to our newsletter for trending solutions and developer bootcamps

            Agree to Sign up and Terms & Conditions

            Share this Page

            share link