seqr | web-based analysis tool for rare disease genomics | Continuous Deployment library

 by   macarthur-lab Python Version: v0.3.0 License: AGPL-3.0

kandi X-RAY | seqr Summary

kandi X-RAY | seqr Summary

seqr is a Python library typically used in Devops, Continuous Deployment, Docker applications. seqr has no bugs, it has no vulnerabilities, it has build file available, it has a Strong Copyleft License and it has low support. You can download it from GitHub.

seqr consists of the following components: - postgres - SQL database used by seqr to store project metadata and user-generated content such as variant notes, etc. - elasticsearch - NoSQL database used to store variant callsets. - redis - in-memory cache used to speed up request handling. - seqr - the main client-server application built using react.js, python and django. - pipeline-runner - optional container for running hail pipelines to annotate and load new datasets into elasticsearch. If seqr is hosted on google cloud (GKE or GCE), Dataproc spark clusters can be used instead. - kibana - optional dashboard and visual interface for elasticsearch.
Support
    Quality
      Security
        License
          Reuse

            kandi-support Support

              seqr has a low active ecosystem.
              It has 97 star(s) with 50 fork(s). There are 13 watchers for this library.
              OutlinedDot
              It had no major release in the last 12 months.
              There are 53 open issues and 738 have been closed. On average issues are closed in 64 days. There are 3 open pull requests and 0 closed requests.
              It has a neutral sentiment in the developer community.
              The latest version of seqr is v0.3.0

            kandi-Quality Quality

              seqr has 0 bugs and 0 code smells.

            kandi-Security Security

              seqr has no vulnerabilities reported, and its dependent libraries have no vulnerabilities reported.
              seqr code analysis shows 0 unresolved vulnerabilities.
              There are 0 security hotspots that need review.

            kandi-License License

              seqr is licensed under the AGPL-3.0 License. This license is Strong Copyleft.
              Strong Copyleft licenses enforce sharing, and you can use them when creating open source projects.

            kandi-Reuse Reuse

              seqr releases are available to install and integrate.
              Build file is available. You can build the component from source.
              Installation instructions are available. Examples and code snippets are not available.

            Top functions reviewed by kandi - BETA

            kandi's functional review helps you automatically verify the functionalities of the libraries and avoid rework.
            Currently covering the most popular Java, JavaScript and Python libraries. See a Sample of seqr
            Get all kandi verified functions for this library.

            seqr Key Features

            No Key Features are available at this moment for seqr.

            seqr Examples and Code Snippets

            No Code Snippets are available at this moment for seqr.

            Community Discussions

            QUESTION

            Multiproceccing + PyMongo lead to [Errno 111]
            Asked 2021-Jul-01 at 17:45

            Good day!

            I've just started playing around with pymongo and multiprocessing. I have received a multicore unit for my experiments, which runs Ubuntu 18.04.4 LTS, codename: bionic. Just for the sake of experiment I have tried it both with python 3.8 and python 3.10, unfortunately the results are similar:

            ...

            ANSWER

            Answered 2021-Jul-01 at 17:45

            Each process needs to have its own client, therefore you most likely need to create the client in each process instead of creating one prior to invoking multiprocessing.

            Forked process: Failure during socket delivery: Broken pipe contains general information on how MongoDB drivers handle forking.

            Source https://stackoverflow.com/questions/68180176

            QUESTION

            Changing an input parameter within React component
            Asked 2021-Apr-29 at 14:54

            I am going through the code of a project and I see the following code:

            ...

            ANSWER

            Answered 2021-Apr-29 at 14:54

            url is a local variable. Reassigning that variable, which is all this code is doing to it, has no possibility of affecting code outside of this function call. It doesn't make the function impure.

            Now, if you were passed in an object, and you started mutating that object, then that would break purity. Because if the component that passed you this object is still using it, then it can "see" that change. For example:

            Source https://stackoverflow.com/questions/67319712

            QUESTION

            Update a string parameter in Elasticsearch _mapping
            Asked 2021-Feb-24 at 14:24

            I have such a _mapping in Elasticsearch 6.8:

            ...

            ANSWER

            Answered 2021-Feb-24 at 14:24

            _meta is a reserved field for storing application-specific metadata. It's not meant to be searchable and can be only retrieved through the GET Mapping API.

            This means that if your _meta content was intended to be consistent with what the _meta field is designed for, you cannot apply any mappings to it. It's a "final" hashmap of concrete values and would need to be defined at the top level of your update-mapping payload:

            Source https://stackoverflow.com/questions/66339967

            QUESTION

            Prevent redux-form from destruction/updating
            Asked 2020-Jun-16 at 16:36

            I am using redux-form and at some point destroy event is fired probably due to some state change, hard to say. I am using redux-dev-tools and there, if I eliminate this event, it fixes the behavior of the form. If I look into trace (redux-dev-tools) section of the destroy event it does not show any of my code, so I am having real trouble tracing it down. I am looking for either a way to trace down what is the root reason for the destroy event in my code or just prevent all form updates after Submit button is hit.

            The actual issue is documented here: https://github.com/macarthur-lab/seqr/issues/1334

            ...

            ANSWER

            Answered 2020-Jun-16 at 16:35

            From these 2 threads:

            https://github.com/redux-form/redux-form/issues/2982

            https://github.com/redux-form/redux-form/issues/603#issuecomment-295043224

            I figured to supply destroyOnUnmount: false property to my redux form and it worked. To prevent saving form details when we go away from page and go back, I added enableReinitialize parameter also.

            Source https://stackoverflow.com/questions/62286658

            QUESTION

            spark-submit error: Invalid maximum heap size: -Xmx4g --jars, but enough of memory on the system
            Asked 2020-Feb-11 at 00:50

            I am running a spark job:

            ...

            ANSWER

            Answered 2020-Feb-11 at 00:50

            Just posted the question and fixed it right away although was pretty desperate. The issue was that I was copy pasting the command in several editors and back and some wrong characters probably were present after --driver-memory 4g. I just deleted spaces (that may not have been spaces) and reinserted them, and it started working. It shard to say why, maybe tab or newline messed it up somehow. I was using Microsoft One Note - maybe it is doing some modifications of spaces...

            Source https://stackoverflow.com/questions/60160477

            QUESTION

            Biopython: is there a one-liner to extract the amino acid sequence of a specific chain from a PDB file?
            Asked 2020-Feb-10 at 10:38

            I want to extract the single letter amino acid sequence of specific chains from a bunch of PDB files.

            I'm able to do it using SeqIO.parse() but it feels quite unpythonic in my opinion:

            ...

            ANSWER

            Answered 2020-Feb-10 at 10:38

            Expanding on @BioGeek answer, here is the equivalent code to extract the sequence when using PDBParser.get_structure() instead of SeqIO.parse()

            Source https://stackoverflow.com/questions/59826385

            Community Discussions, Code Snippets contain sources that include Stack Exchange Network

            Vulnerabilities

            No vulnerabilities reported

            Install seqr

            The seqr production instance runs on Google Kubernetes Engine (GKE) and data is loaded using Google Dataproc Spark clusters. On-prem installs can be created using docker-compose: [Local installs using docker-compose](deploy/LOCAL_INSTALL.md).

            Support

            For any new features, suggestions and bugs create an issue on GitHub. If you have any questions check and ask questions on community page Stack Overflow .
            Find more information at:

            Find, review, and download reusable Libraries, Code Snippets, Cloud APIs from over 650 million Knowledge Items

            Find more libraries
            CLONE
          • HTTPS

            https://github.com/macarthur-lab/seqr.git

          • CLI

            gh repo clone macarthur-lab/seqr

          • sshUrl

            git@github.com:macarthur-lab/seqr.git

          • Stay Updated

            Subscribe to our newsletter for trending solutions and developer bootcamps

            Agree to Sign up and Terms & Conditions

            Share this Page

            share link