REPTILE | Predicting regulatory DNA elements | Genomics library
kandi X-RAY | REPTILE Summary
kandi X-RAY | REPTILE Summary
REPTILE is a tool to identify enhancers by epigenomic data (DNA methylation and histone modifications). There two key concepts in REPTILE, "query region" and "DMR":. The currently known enhancers (~2kb) are generally much larger than the binding motifs of TFs (~10-20bp) and are likely to include sequences that contribute little to their enhancer activity. We used the term “query region” to describe such large regions where a small fraction of the region is regulatory (if any). Query region also refers to negative regions (that showed no observable enhancer activity) and the genomic windows used by enhancer prediction methods. Since large portion of an active query region is likely to have little contribution to its enhancer activity, the epigenomic signature of the whole active query region may not be a good approximation to the epigenomic state of the bona fide regulatory sequences within it. To address this issue, we used differentially methylated regions (DMRs, ~500bp) to pinpoint the possible regulatory sub-regions within query regions. DMRs serve as high-resolution enhancer candidates and may capture the local epigenomic patterns that would otherwise be averaged/washed out in analysis focusing on the query regions.
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Top functions reviewed by kandi - BETA
- Retrieve an epimark profile
- Print error message
- Return a list of the indices of the peak in a given block
- Prints the error message
REPTILE Key Features
REPTILE Examples and Code Snippets
Community Discussions
Trending Discussions on REPTILE
QUESTION
The xml format is a good way to store any hierarchical data. As an example we are using the classification of animals
...ANSWER
Answered 2021-May-28 at 10:32What we can see in the html table, is that the first row holds a cell for every hierarchy level which is represented as a column. This means it has to be generated a row with all elements from the highest till the deepest hierarchy level. The element on the deepest hierarchy level is the one without further descendants. To get these we can use this xpath expression
QUESTION
I am trying to style Typography from Material UI with a CSS file but the styling I do does not get applied to my React website. Any help would be mich appreciated!
I want to style the Typography with className ".title-card", and below you will find the corresponding js and css files
...ANSWER
Answered 2021-May-12 at 18:19Remove . from className=".title-card":
QUESTION
How do you wrap text around an image in HTML and CSS? I have an image and a text next to it, but it would not go below the image. how could I make text go around the image? What would be the best way for the text and image to looks when we view on a phone screen.
I cannot any useful way on the internet. I am quite new to html
Thank you.
here is my code bellow
...ANSWER
Answered 2021-May-09 at 22:34To make the time below the image, remove
QUESTION
I'm using material-ui library to create card like items. I have the list of items stored in a js file like this:-
...ANSWER
Answered 2021-May-09 at 22:24You could try this, you have to loop at every item and render a component.
QUESTION
I could not build up the solution how to find the previous element without specific pattern.
Description: In the select option below is a simple Select box. The parent items have no - or dash, and the parents are created, then the children option values, so always, the children option values have greater value than parent value.
I am trying to find the parent value if a element is selected, if the element selected is parent, then return the parent value.
This is simple and obvious problem but I could not figure out the problem, if anyone could show how to get the above.
The html is from CMS - Drupal the html can not be changed
...ANSWER
Answered 2021-Apr-23 at 14:47This code will get you the parent value on child options if that's what you wanted.
QUESTION
I am creating a word app to study English vocabulary. It is based on a very large Word Bank that I plan to keep in a list. (Hard coded).
This large list is made up of Word Objects :
...ANSWER
Answered 2021-Apr-13 at 12:00multiDexEnabled is needed when over 64 thousand JVM methods are referenced in an app. It isn't related to the size of any hardcoded data, or anything related to Dart at all.
It shouldn't be an issue, but if you wish to avoid it, there are some documented things to try on the Android Developer website.
On another note, since your data is hardcoded, try to use const where you can.
QUESTION
This is the sample code of the Card from material-ui. How can I make the picture inside the card media to somehow pop out a bit when the mouse hovers on it? Or like a zoom once the mouse hovers on that picture
...ANSWER
Answered 2021-Apr-01 at 06:08You can use the 'hover' mediaquery. Here you can find an example that I made base on your code SandBox
QUESTION
Why my code gets returned after scanning 1st char?
Code:
...ANSWER
Answered 2021-Mar-24 at 14:30Because scanf doesn't consume the newline, so you can use getchar() after the first scanf to swallow it.
QUESTION
I have two arrays of objects.
$animals contains one object per animal with the properties 'id', 'sort' and 'alive' ("yes" or "no).
$inventory contains a matching object for every animal (matched on 'id') in $animals with the information (properties) 'id', 'type' and 'validated' ($true or $false).
I'd like to loop through all of my animals in $animals where "alive=yes" and:
- Do nothing if "type=reptile" in $inventory.
- Send animals to the vet where "validated=$false" in $inventory.
The code:
...ANSWER
Answered 2021-Mar-15 at 18:37Believe it or not, a foreach or for loop with an if condition is the fastest way there is in Powershell to filter arrays and where-object is the slowest.
As Lee_Dailey pointed out in the comment, in my opinion, the most elegant way is to merge both arrays but in this case and for your example this works fine considering that the count of $animals and $inventory will always be the same and both arrays will always be ordered by ID:
QUESTION
Say I had an interface that described a library that items that look like this:
ANSWER
Answered 2021-Mar-13 at 22:59If I understand you right, you want this: How to create enum like type in TypeScript? and then specify MyItem as
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