A set of tools written in Perl and C++ for working with VCF files, such as those generated by the 1000 Genomes Project.
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Plot structural variant signals from many BAMs and CRAMs
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Source repository for fiat tokens on the CENTRE network.
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Java utilities for Bioinformatics
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SmartBugs: A Framework to Analyze Ethereum Smart Contracts
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Structural variation caller using third generation sequencing
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Copy number variant detection from targeted DNA sequencing
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A comprehensive library for computational molecular biology
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SeqAn's official repository.
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Official repository for the QIIME 2 framework.
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COBRApy is a package for constraint-based modeling of metabolic networks.
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Gene Set Enrichment Analysis in Python
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Software package for assigning SARS-CoV-2 genome sequences to global lineages.
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Deep generative modeling for single-cell omics data
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Accurate sample inference from amplicon data with single nucleotide resolution
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A fast multi-threaded k-mer counter
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single-cell-best-practicesby theislab
Jupyter Notebook 
386
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https://www.sc-best-practices.org
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Efficient pythonic random access to fasta subsequences
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:scissors: :zap: Rapid haploid variant calling and core genome alignment
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C/C++ to assembly visualizer
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The Ensembl Variant Effect Predictor predicts the functional effects of genomic variants
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An analysis and visualization platform for 'omics data
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A wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for RRBS data
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Quickly search, compare, and analyze genomic and metagenomic data sets.
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A list of scRNA-seq analysis tools
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Mummer alignment tool
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Summarize, Analyze and Visualize MAF files from TCGA or in-house studies.
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Prodigal Gene Prediction Software
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NicheNet: predict active ligand-target links between interacting cells
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A repository of bioinformatic scripts, SOPs, and tutorials for analyzing microbiome data.
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Haplotype VCF comparison tools
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DELLY2: Structural variant discovery by integrated paired-end and split-read analysis
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Inclusive model of expression dynamics with conventional or metabolic labeling based scRNA-seq / multiomics, vector field reconstruction and differential geometry analyses
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Data and analysis for NA12878 genome on nanopore
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RSEM: accurate quantification of gene and isoform expression from RNA-Seq data
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Performant Pythonic GenomicRanges
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Hifiasm: a haplotype-resolved assembler for accurate Hifi reads
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Structural variant and indel caller for mapped sequencing data
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Performant Pythonic GenomicRanges
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Graph-based alignment (Hierarchical Graph FM index)
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GTDB-Tk: a toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes.
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Tools for fast and flexible genome assembly scaffolding and improvement
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RNA Velocity generalized through dynamical modeling
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The modern C++ library for sequence analysis. Contains version 3 of the library and API docs.
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Python functions for reading kaldi data formats. Useful for rapid prototyping with python.
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Customizable workflows based on snakemake and python for the analysis of NGS data
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A One-Click System for Analyzing Loop-Resolution Hi-C Experiments
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Proof-of-concept seq-to-graph mapper and graph generator
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UICollectionView layout for presenting of the overlapping cells.
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genes and genomes at your fingertips
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v
vcftoolsby vcftools
A set of tools written in Perl and C++ for working with VCF files, such as those generated by the 1000 Genomes Project.
C++
420
Updated: 2 y ago
License: Weak Copyleft (LGPL-3.0)
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samplotby ryanlayer
Plot structural variant signals from many BAMs and CRAMs
Python
418
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License: Permissive (MIT)
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centre-tokensby centrehq
Source repository for fiat tokens on the CENTRE network.
JavaScript
418
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jvarkitby lindenb
Java utilities for Bioinformatics
Java
416
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smartbugsby smartbugs
SmartBugs: A Framework to Analyze Ethereum Smart Contracts
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412
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Snifflesby fritzsedlazeck
Structural variation caller using third generation sequencing
Python
410
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cnvkitby etal
Copy number variant detection from targeted DNA sequencing
Python
406
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biotiteby biotite-dev
A comprehensive library for computational molecular biology
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405
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qiime2by qiime2
Official repository for the QIIME 2 framework.
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394
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c
cobrapyby opencobra
COBRApy is a package for constraint-based modeling of metabolic networks.
Jupyter Notebook
394
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GSEApyby zqfang
Gene Set Enrichment Analysis in Python
Python
392
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pangolinby cov-lineages
Software package for assigning SARS-CoV-2 genome sequences to global lineages.
Python
389
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scVIby YosefLab
Deep generative modeling for single-cell omics data
Python
388
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dada2by benjjneb
Accurate sample inference from amplicon data with single nucleotide resolution
R
388
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Jellyfishby gmarcais
A fast multi-threaded k-mer counter
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388
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single-cell-best-practicesby theislab
https://www.sc-best-practices.org
Jupyter Notebook
386
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pyfaidxby mdshw5
Efficient pythonic random access to fasta subsequences
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384
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snippyby tseemann
:scissors: :zap: Rapid haploid variant calling and core genome alignment
Perl
384
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c
cpp-to-assemblyby ynh
C/C++ to assembly visualizer
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380
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ensembl-vepby Ensembl
The Ensembl Variant Effect Predictor predicts the functional effects of genomic variants
Perl
374
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a
anvioby merenlab
An analysis and visualization platform for 'omics data
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369
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T
TrimGaloreby FelixKrueger
A wrapper around Cutadapt and FastQC to consistently apply adapter and quality trimming to FastQ files, with extra functionality for RRBS data
Perl
368
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sourmashby sourmash-bio
Quickly search, compare, and analyze genomic and metagenomic data sets.
Python
368
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scRNA-seq_notesby mdozmorov
A list of scRNA-seq analysis tools
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362
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maftoolsby PoisonAlien
Summarize, Analyze and Visualize MAF files from TCGA or in-house studies.
R
356
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Prodigalby hyattpd
Prodigal Gene Prediction Software
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354
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nichenetrby saeyslab
NicheNet: predict active ligand-target links between interacting cells
R
353
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microbiome_helperby LangilleLab
A repository of bioinformatic scripts, SOPs, and tutorials for analyzing microbiome data.
Python
352
Updated: 4 y ago
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h
hap.pyby Illumina
Haplotype VCF comparison tools
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349
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dellyby dellytools
DELLY2: Structural variant discovery by integrated paired-end and split-read analysis
C++
347
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d
dynamo-releaseby aristoteleo
Inclusive model of expression dynamics with conventional or metabolic labeling based scRNA-seq / multiomics, vector field reconstruction and differential geometry analyses
Python
345
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NA12878by nanopore-wgs-consortium
Data and analysis for NA12878 genome on nanopore
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344
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R
RSEMby deweylab
RSEM: accurate quantification of gene and isoform expression from RNA-Seq data
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344
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pyrangesby pyranges
Performant Pythonic GenomicRanges
Python
343
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h
hifiasmby chhylp123
Hifiasm: a haplotype-resolved assembler for accurate Hifi reads
C++
342
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mantaby Illumina
Structural variant and indel caller for mapped sequencing data
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342
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pyrangesby biocore-ntnu
Performant Pythonic GenomicRanges
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340
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h
hisat2by DaehwanKimLab
Graph-based alignment (Hierarchical Graph FM index)
C++
339
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GTDBTkby Ecogenomics
GTDB-Tk: a toolkit for assigning objective taxonomic classifications to bacterial and archaeal genomes.
Python
337
Updated: 2 y ago
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R
RagTagby malonge
Tools for fast and flexible genome assembly scaffolding and improvement
Python
336
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scveloby theislab
RNA Velocity generalized through dynamical modeling
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334
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seqan3by seqan
The modern C++ library for sequence analysis. Contains version 3 of the library and API docs.
C++
334
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k
kaldi-io-for-pythonby vesis84
Python functions for reading kaldi data formats. Useful for rapid prototyping with python.
Python
332
Updated: 4 y ago
License: Permissive (Apache-2.0)
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snakepipesby maxplanck-ie
Customizable workflows based on snakemake and python for the analysis of NGS data
Python
327
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j
juicerby aidenlab
A One-Click System for Analyzing Loop-Resolution Hi-C Experiments
Shell
327
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minigraphby lh3
Proof-of-concept seq-to-graph mapper and graph generator
C
326
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StickyCollectionView-Swiftby matbeich
UICollectionView layout for presenting of the overlapping cells.
Swift
326
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genomepyby vanheeringen-lab
genes and genomes at your fingertips
Python
324
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