Ribbon | genome browser that shows long reads | Genomics library

I want to design and train a neural network for the automatic recognition of the edges, in some microscopic images. I am using Keras for a start, I may consider PyTorch later.

The structure of the images is rather simple, with some dark areas, and some clear areas, relatively easy to distinguish, and the task is to select the pixels of the contour between dark and clear areas. The transition between dark and clear is gradual, so my result is not a single line of edge pixels, but rather a 10 or 15 pixels wide "ribbon" at the edge.

I have manually annotated 200-something images, so for each image I have another image, of the same size, where the pixels of the contours are black, and all the other pixels are white.

I have seen many tutorials on how to design, compile and fit a model (a neural network), and then how to test it, using the manually annotated data.

However, most of the tutorials work on problems of classification, where the number of neurons in the output layer is the number of categories.

My problem is not a problem of classification, and ideally my output should be an image of the same size of the input.

So, here is my question:

What is the best way to design the output layer? Is a layer with a number of neurons equal to the number of pixels the best idea? Or this is a waste, and there is a more efficient way?

Addendum

1. The images are "easy", but it is still difficult to find the contour pixels, so I believe that it is worth using the machine learning approach.
2. The transition between dark and clear is a little gradual, so my result is not a single line of pixels on the edge, but rather a band, a 10 or 15 wide ribbon of edge pixels. Since I am after a ribbon of pixels, my categories should be "edge" and "not-edge". If I use the categories "dark pixels" and "clear pixels", and then numerically find the pixels between the two areas I do not get the "ribbon" result, which I need.

I have a Microsoft Access (Office 365) form. I need the controls to be neatly placed on the form.

For example, in the Access Form Design View below, the "Residential" label and the rectangle around the checkbox both have the same Left and Width. The Left property was set by using the Align - Left option of the Sizing & Ordering group of the Arrange ribbon tab.

• I have looked at the padding and margins for each control. This has no effect on control placement.

• Is there a way to compute the Top and Left placement for a control? I tried Top + Height + 2*BorderHeight with all padding and margins set to 0. This did not improve the situation.

• One of the biggest problems is the absence of support to precisely position controls independently from the labels.

• Is there a third-party tool that can be used to design Access forms? Form layout seems to be time-consuming aspect of Access.

I'm developing an office-js add-in that needs to run automatically (without user interaction) every time any Excel document starts. I have configured it to use a shared runtime. This capability exists for VSTO add-in which load when Excel starts but seems to be missing for Office-js addins.

I only found two possible solutions, but they don't work that well:

1. When the add-in runs for the first time in a document, set Office.addin.setStartupBehavior(Office.StartupBehavior.load) so that the add-in loads automatically for the document.

Issue: the add-in needs to be manually inserted once (the user needs to click on the add-in ribbon once per document). This setting only applies to the current document. Not practical since users first need to interact with the add-in for every new document.

1. As Excel opens a new document, use a VSTO add-in to insert the add-in by editing the document using OpenXML following this article https://docs.microsoft.com/en-us/office/dev/add-ins/develop/run-code-on-document-open.

Issue: Excel blocks I/O for documents as they are opened. For local documents, I found a way to write onto them as Excel writes on them, but when the documents are saved on OneDrive, any stream with ReadWrite attributes can't get access. So this solution is not working very well.

Is there a workaround possible?

I'm currently working on a microservices application for my internship using Consul for service discovery and feign clients for communicating between the services. When we started working on the existing project which already was built using microservices, we upgraded Spring boot to 2.4.3 & cloud to 2020.0.1, so that we could make use of Java 15 to use records instead of normal classes for dtos. The problem we have now is that, whenever we make a call to a composite service, that will try to retrieve data from multiple services (for example users and teams service), that we get the following stacktrace:

Do you know why this function called from my script commands.ts which is a script used by the commands in the ribbon wouldn't work?

I am creating an Add-in for Outlook and I am calling the method "join" which is triggered when the button from the ribbon is clicked. The issue I am having is that when I am in the browser the method "replaceAsync" never gets called so the notification is never added to the screen. If I run the application in Outlook desktop the notification shows absolutely fine (image 1). This is the method I am using, could you advise if what I am doing is correct and do you know what could be reason that is causing this issue in the browser?

Many Thanks

Image displaying notification in Outlook Desktop app

I have an Excel spreadsheet - a lot of them actually - that have drop-down selections in them. I want to automate filling them in, selecting an option from the list.

When I inspect the cell that has the drop-down in Excel itself, I cannot click on Validation in the Data Tools ribbon section as it is greyed out. I think the sheet has protection.

When I inspect the cell in VBA, the Validation.Formula1 property contains a string like "=list_b1191f893baa0c18600db155cc008dd2_label".

How can I find the contents of this list in VBA so that I can pick one of the valid values?

Can the Microsoft Office Ribbon be coded into a non-Office Windows Forms application for VB? If so, how?

I searched both here and on Google, but found only topics related to Office apps and add-ins, and nothing regarding non-Office use.

I am going through the walkthrough on how to create your first outlook addin using the ribbon designer: https://docs.microsoft.com/en-us/visualstudio/vsto/walkthrough-creating-your-first-vsto-add-in-for-outlook?view=vs-2019

My goal is to make reply templates that includes the sender's name in the greeting.

From researching the issue, I believe I need either MailItem.SenderEmailAddress or MailItem.Sender but when I tried to add it to the mailitem.htmlbody it doesn't show anything at all.

Here is the code I have for my test.

In my project I'm using Jhipster Spring Boot and I would like to start 2 instances of one microservise at the same time, but on different instances of a database (MongoDB).

In this microservice I have classes, services, rests that are used for collections A, B C,.. for which now I would like to have also history collections A_history, B_history, C_history (that are structured exactly the same like A, B, C) stored in separated instance of a database. It makes no sense to me to create "really separated" microservice since I would have to copy all logic from the first one and end up with doubled code that is very hard to maintain. So, the idea is to have 2 instances of the same microservice, one for A, B, C collections stored in "MicroserviceDB" and second for A_history, B_history, C_history collections stored in "HistoryDB".

I've tried with creating 2 profiles, but when I start from a command line History microservice, it is started ok, but if I also try to start "original" microservice at the same time, it is started but immediately history service becomes "original" microservice. Like they cannot work at the same time.

Is this concept even possible in microservice architecture? Does anyone have an idea how to make this to work, or have some other solution for my problem?

Thanks.

application.yml