ALEC | NonCommercial 3.0 United States license | Genomics library
kandi X-RAY | ALEC Summary
kandi X-RAY | ALEC Summary
Amplicon Long-read Error Correction (ALEC) was developed to correct sequencing and alignment errors [substitutionsandinsertion/deletions (indels)] generated by targeted amplicon sequencing with the PacBio RS platform. This script has been developed usingPacBio single molecule real time (SMRT) full-gene sequencing of the CYP2D6 gene (5.0 kb)according to the P6-C4 Pacific Biosciences protocol. ALEC was further tested using a 9.2kb amplicon and long-read PacBio SMRT sequencing of the RYR2 gene. ALEC may have utility withother long-read sequencing platforms (e.g., Oxford Nanopore), and/or other sequencing chemistries; however, optimizing the error correction parameters may be necessary to achieve ideal sequence correction and output for genes and sequencing platforms other than those noted above. Four types of sequencing errors can be corrected after applying ALEC: 1) random substitutions; 2) random indels; 3) indels within homopolymers; and 4) indels near sequence variants.
Support
Quality
Security
License
Reuse
Top functions reviewed by kandi - BETA
- Parse a Seq
- Performs the correct correction of the reads .
- Argument parser .
- Calculates long distances .
- Check if the insertion rate is correct
- Fix deletion .
- Parse a fasta file
- Calculates allele frequency frequencies .
- Calculate consensus insert frequency .
- Extract the feature matrix from the given reads .
ALEC Key Features
ALEC Examples and Code Snippets
Community Discussions
Trending Discussions on ALEC
QUESTION
Here is my code
...ANSWER
Answered 2021-Jun-14 at 21:50Create a CTE that returns for each Block_id
the step
of the first John
.
Then join the table to the CTE:
QUESTION
I have the following dataframe
...ANSWER
Answered 2021-Jun-14 at 14:44One method uses an updatable CTE:
QUESTION
I want to be able to determine if a passed argument is an IEnumerable.
...ANSWER
Answered 2021-Jun-11 at 15:31It isn't So: while it isn't IEnumerable, because
KeyValuePair
is a value-type (struct
), and generic variance rules doesn't allow for value-types and object
to be interchangeable during type tests (as a conversion - boxing - is required).
IEnumerable, it is, however,
IEnumerable
in the non-generic sense.
QUESTION
I have a movieDetails.json database and the collection name is a movie then our teacher wants us to Display the number of movies based on the number of directors a movie has a. Hint you might have to use the javascript function split Since the director is not an array, it is only a string so I can't count how many directors are there because it will always come out as 1 since its a string so I want to split that string so that I can get an array so that I can count it. But unfortunately, I don't know the query that will solve this problem. ex. of expected output:
...ANSWER
Answered 2021-Apr-28 at 11:45Demo - https://mongoplayground.net/p/y3kvFnocWKn
Use aggregation query
Read the below links for better understanding
QUESTION
I am trying to insert an element into the first column of each row in a table of data read from a text file.
...ANSWER
Answered 2021-Apr-25 at 14:48You need to use for loop using index rather then comprehension
QUESTION
I know there's A way to do this, but I'm curious to know if there is a "best" way of doing this...
Let's say I have this table
Name Date Value Troy 2021-04-21 1 Troy 2021-04-20 2 Troy 2021-04-19 3 Alec 2021-04-21 3 Alec 2021-04-20 4 Alec 2021-04-19 5I want to reorder the table based on the average of the "Value" column for each person.
Here is the expected output:
Name Date Value Alec 2021-04-21 3 Alec 2021-04-20 4 Alec 2021-04-19 5 Troy 2021-04-21 1 Troy 2021-04-20 2 Troy 2021-04-19 3Is there a most efficient way of executing this?
...ANSWER
Answered 2021-Apr-21 at 18:36The calculation of the average value can be done either by aggregation in a query that groups by person and then it is joined to the table, or with AVG()
window function which can be used directly in the ORDER BY
clause and I believe is better for performance:
QUESTION
This is a challenging one for me tried for hours as I am learning but I am not sure if my logic is correct at all.
Define a function called stars that takes in two dictionaries:
movies: a dictionary where the keys are movie titles and
the values are lists of major performers in the movie.
For example:
ANSWER
Answered 2021-Apr-10 at 19:04I believe you need.
QUESTION
This question is more about code organisation rather than an error/bug problem.
I am working on request body validation, json has structure like:
...ANSWER
Answered 2021-Mar-17 at 21:09the good practice here is that you are validating inputs ✅
the downside of your current approach is that it is hard to maintain long term ❌
you could go down the middleware way, and create multiple middlewares for each route/body that you need to validate. It works, but, the amount of work and maintenance burden will increase over time.
one approach you can follow is to create an expected schema of your input (e.g. a model definition describing the fields and values expected), and use a validator to check the current input based on the schema you created.
for Node.js we have multiple tools for that like: AJV, JOI, YUP.
using a sample example with JOI, you could replace your validation flow by doing:
QUESTION
I am trying to access the 'title' from the following list but it keeps throwing error.
...ANSWER
Answered 2020-Oct-28 at 14:54You need to make a cast on the element of your movie list.
QUESTION
the burger menu I've created using plain HTML, CSS, and JS does not open when clicked and I am at a loss for what to try next. The goal is for the burger menu to show up in mobile view and use 100% of the screens width to display the navigation when toggled. Here is a codepen with my code as well. https://codepen.io/alec-johnson/pen/dyMgKeN
...ANSWER
Answered 2020-Sep-19 at 15:29Remove .navabr-links
here
.navabr-links.active {display: flex;}
so it will be.active {display: flex;}
Community Discussions, Code Snippets contain sources that include Stack Exchange Network
Vulnerabilities
No vulnerabilities reported
Install ALEC
You can use ALEC like any standard Python library. You will need to make sure that you have a development environment consisting of a Python distribution including header files, a compiler, pip, and git installed. Make sure that your pip, setuptools, and wheel are up to date. When using pip it is generally recommended to install packages in a virtual environment to avoid changes to the system.
Support
Reuse Trending Solutions
Find, review, and download reusable Libraries, Code Snippets, Cloud APIs from over 650 million Knowledge Items
Find more librariesStay Updated
Subscribe to our newsletter for trending solutions and developer bootcamps
Share this Page